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Gene Review

zmp-1  -  Protein ZMP-1

Caenorhabditis elegans

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High impact information on zmp-1

  • This pattern of vulval cell types is likely to depend on the cis-regulatory regions of the transcriptional targets of intercellular signals in vulval development. egl-17, zmp-1, and cdh-3 are expressed differentially in the developing vulva cells, providing a potential readout for different signaling pathways [1].
  • In previous work, we reported analysis of the C. elegans dpy-31 locus, encoding a hypodermally expressed zinc-metalloprotease of the BMP-1/TOLLOID family essential for viability and cuticle deposition [2].
  • Full-length or partial coding sequences of 4 different zinc-metalloprotease cDNAs of Ostertagia (met-1, -2, -3 and -4) were amplified using gene-specific primers using the 3'- and 5'-Rapid Amplification of cDNA Ends (RACE) technique [3].


  1. cis-Regulatory control of three cell fate-specific genes in vulval organogenesis of Caenorhabditis elegans and C. briggsae. Kirouac, M., Sternberg, P.W. Dev. Biol. (2003) [Pubmed]
  2. The C Terminus of Collagen SQT-3 Has Complex and Essential Functions in Nematode Collagen Assembly. Novelli, J., Page, A.P., Hodgkin, J. Genetics (2006) [Pubmed]
  3. Molecular analysis of astacin-like metalloproteases of Ostertagia ostertagi. De Maere, V., Vercauteren, I., Geldhof, P., Gevaert, K., Vercruysse, J., Claerebout, E. Parasitology (2005) [Pubmed]
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