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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

efn-4  -  Protein EFN-4

Caenorhabditis elegans

 
 
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High impact information on efn-4

  • We show that efn-4 also functions in embryonic morphogenesis, and that it is expressed in the developing nervous system [1].
  • In efn-4 and mab-20 mutants, ectopic contacts form between cells belonging to different rays [2].
  • In egl-5 mutants, efn-4 reporter expression in certain ray cells was increased, inconsistent with a simple repulsion model for efn-4 action [2].

References

  1. The divergent C. elegans ephrin EFN-4 functions inembryonic morphogenesis in a pathway independent of the VAB-1 Eph receptor. Chin-Sang, I.D., Moseley, S.L., Ding, M., Harrington, R.J., George, S.E., Chisholm, A.D. Development (2002) [Pubmed]
  2. The roles of an ephrin and a semaphorin in patterning cell-cell contacts in C. elegans sensory organ development. Hahn, A.C., Emmons, S.W. Dev. Biol. (2003) [Pubmed]
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