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Gene Review

lag-1  -  Protein LAG-1

Caenorhabditis elegans

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High impact information on lag-1


Biological context of lag-1

  • We recovered mutations in five new genes, named ego (enhancer of glp-1), and two previously identified genes, lag-1 and glp-4, that strongly enhance a weak glp-1 loss-of-function phenotype in the germline [2].


  1. lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H). Christensen, S., Kodoyianni, V., Bosenberg, M., Friedman, L., Kimble, J. Development (1996) [Pubmed]
  2. Enhancers of glp-1, a gene required for cell-signaling in Caenorhabditis elegans, define a set of genes required for germline development. Qiao, L., Lissemore, J.L., Shu, P., Smardon, A., Gelber, M.B., Maine, E.M. Genetics (1995) [Pubmed]
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