Gene Review:
egl-21 - Protein EGL-21
Caenorhabditis elegans
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High impact information on egl-21
- We provide evidence that egl-3 PC2 and egl-21 CPE mutants have diminished acetylcholine release at neuromuscular junctions (NMJs) [1].
Associations of egl-21 with chemical compounds
- Taken together, these results suggest that egl-21 CPE and egl-3 PC2 process endogenous neuropeptides that facilitate acetylcholine release at C. elegans NMJs [1].
Other interactions of egl-21
- Mutants lacking either egl-21 CPE or egl-3, which encodes the C. elegans ortholog of PC type 2 (PC2), were defective for processing endogenously expressed FMRFamide (Phe-Met-Arg-Phe-NH2)-related peptides (FaRPs) [1].
References
- The EGL-21 carboxypeptidase E facilitates acetylcholine release at Caenorhabditis elegans neuromuscular junctions. Jacob, T.C., Kaplan, J.M. J. Neurosci. (2003) [Pubmed]
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