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Gene Review

nhr-40  -  Protein NHR-40

Caenorhabditis elegans

 
 
 
 
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High impact information on nhr-40

  • The downregulation of nhr-40 by RNAi, or a mutant with an intronic region deletion, results in late embryonic and early larval arrest with defects in elongation and morphogenesis [1].
  • The nhr-40 loss of function phenotype includes irregular development of body wall muscle cells and impaired movement and coordination resembling neuromuscular affection [1].

References

  1. NHR-40, a Caenorhabditis elegans supplementary nuclear receptor, regulates embryonic and early larval development. Brozov??, E., Simeckov??, K., Kostrouch, Z., Rall, J.E., Kostrouchov??, M. Mech. Dev. (2006) [Pubmed]
 
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