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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

mfb-1  -  Protein MFB-1

Caenorhabditis elegans

 
 
 
 
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High impact information on mfb-1

  • The mfb-1 deletion mutant significantly enhanced the dauer constitutive (Daf-c) phenotype caused by mutations in the DAF-7/TGF-beta-like signalling pathway, but not the DAF-2/insulin receptor-like signalling pathway [1].
  • Conversely, the Daf-c phenotypes of DAF-7 pathway mutants were partially suppressed by mfb-1 cDNA transgenes [1].

References

  1. MFB-1, an F-box-type ubiquitin ligase, regulates TGF-beta signalling. Aoyama, Y., Urushiyama, S., Yamada, M., Kato, C., Ide, H., Higuchi, S., Akiyama, T., Shibuya, H. Genes Cells (2004) [Pubmed]
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