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Gene Review

FBXO25  -  F-box protein 25

Homo sapiens

Synonyms: F-box only protein 25, FBX25
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Disease relevance of FBXO25

  • Therefore, here we have shown that FBXO25 is a novel F-box protein analogous to atrogin-1, which is not involved in muscle atrophy [1].

High impact information on FBXO25


Analytical, diagnostic and therapeutic context of FBXO25

  • Using a RT-PCR, we demonstrated that FBXO25 is highly expressed in brain, kidney, and intestine, whereas atrogin-1 expression is largely restricted to striate muscle [1].


  1. FBXO25, an F-box protein homologue of atrogin-1, is not induced in atrophying muscle. Maragno, A.L., Baqui, M.M., Gomes, M.D. Biochim. Biophys. Acta (2006) [Pubmed]
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