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Gene Review

CELE_F40F9.5  -  Protein F40F9.5

Caenorhabditis elegans

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High impact information on translocase

  • As part of their demise, apoptotic cells disrupt the normal asymmetric distribution of phospholipids across their plasma membranes, an asymmetry normally maintained by an aminophospholipid translocase [1].
  • These translocase complexes cooperate with soluble proteins from the cytosol, the intermembrane space and the matrix [2].


  1. Transbilayer phospholipid movement and the clearance of apoptotic cells. Williamson, P., Schlegel, R.A. Biochim. Biophys. Acta (2002) [Pubmed]
  2. Mechanisms of protein translocation into mitochondria. Voos, W., Martin, H., Krimmer, T., Pfanner, N. Biochim. Biophys. Acta (1999) [Pubmed]
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