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Gene Review

Foxe1  -  forkhead box E1

Rattus norvegicus

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High impact information on Foxe1

  • By gel retardation assays we demonstrated that thapsigargin treatment increases the binding of DREAM to the DRE sequences present in Pax8 and TTF-2/Foxe1 5' UTRs, and this correlates with a significant reduction of the expression of these genes [1].


  1. The transcriptional repressor DREAM is involved in thyroid gene expression. D'Andrea, B., Di Palma, T., Mascia, A., Motti, M.L., Viglietto, G., Nitsch, L., Zannini, M. Exp. Cell Res. (2005) [Pubmed]
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