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Gene Review

Rad23a  -  RAD23a homolog (S. cerevisiae)

Mus musculus

Synonyms: 2310040P19Rik, AL024030, HR23A, Mhr23a, UV excision repair protein RAD23 homolog A, ...
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High impact information on Rad23a

  • In agreement with the results of in vitro repair studies, this indicates that mHR23A can functionally replace mHR23B in NER [1].

Anatomical context of Rad23a

  • In wild-type mouse embryonic fibroblasts (MEFs), endogenous XPC was found to be relatively stable, while its steady-state level and stability appeared significantly reduced by targeted disruption of the mHR23B gene, but not by that of mHR23A [2].


  1. Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B. Ng, J.M., Vrieling, H., Sugasawa, K., Ooms, M.P., Grootegoed, J.A., Vreeburg, J.T., Visser, P., Beems, R.B., Gorgels, T.G., Hanaoka, F., Hoeijmakers, J.H., van der Horst, G.T. Mol. Cell. Biol. (2002) [Pubmed]
  2. Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex. Okuda, Y., Nishi, R., Ng, J.M., Vermeulen, W., van der Horst, G.T., Mori, T., Hoeijmakers, J.H., Hanaoka, F., Sugasawa, K. DNA Repair (Amst.) (2004) [Pubmed]
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