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Gene Review

UNC5CL  -  unc-5 homolog C (C. elegans)-like

Homo sapiens

Synonyms: MGC34763, MUXA, Protein unc-5 homolog C-like, UNC5C-like protein, ZU5 and death domain-containing protein, ...
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High impact information on UNC5CL

  • In reporter gene assays, overexpression of ZUD inhibited NF-kappaB-dependent transcription induced by both tumor necrosis factor (TNF) and interleukin-1 and their downstream signaling proteins [1].


  1. Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB. Zhang, J., Xu, L.G., Han, K.J., Shu, H.B. J. Biol. Chem. (2004) [Pubmed]
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