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Gene Review:

CNKSR2 - connector enhancer of kinase suppressor of...

Homo sapiens

Synonyms: CNK homolog protein 2, CNK2, Connector enhancer of KSR 2, Connector enhancer of kinase suppressor of ras 2, KIAA0902, ...

Lanigan, T.M. et al.

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High impact information on CNKSR2

Our results show that MAPK signaling appears to play a role in the phosphorylation of CNK2 in vivo [1].
In MDCK cells, full-length CNK2 is localized to the lateral plasma membrane [1].

Biological context of CNKSR2

We characterize CNK2 phosphorylation, membrane localization, and interaction with Ras effector molecules [1].

References

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf. Lanigan, T.M., Liu, A., Huang, Y.Z., Mei, L., Margolis, B., Guan, K.L. FASEB J. (2003) [Pubmed]

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