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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CCT5  -  chaperonin containing TCP1, subunit 5...

Homo sapiens

Synonyms: CCT-epsilon, CCTE, HEL-S-69, KIAA0098, T-complex protein 1 subunit epsilon, ...
 
 
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High impact information on CCT5

  • In contrast to CCT epsilon, no significant light regulation of CCT alpha was found in the mesocotyl [1].
  • Data collected included clinical information, viral load, and CD4T lymphocyte percentage (CD4%) at baseline and 24, 48, and 96 weeks after PTI [2].
  • Treatment of MCF-7 cells with siRNA specific for CCT5, RGS3, or YKT6 resulted in a significant enhancement of docetaxel-induced apoptosis [3].

References

  1. Developmental and light-dependent changes of the cytosolic chaperonin containing TCP-1 (CCT) subunits in maize seedlings, and the localization in coleoptiles. Himmelspach, R., Nick, P., Schäfer, E., Ehmann, B. Plant J. (1997) [Pubmed]
  2. Partial treatment interruption of protease inhibitor-based highly active antiretroviral therapy regimens in HIV-infected children. Abadi, J., Sprecher, E., Rosenberg, M.G., Dobroszycki, J., Sansary, J., Fennelly, G., Wiznia, A. J. Acquir. Immune Defic. Syndr. (2006) [Pubmed]
  3. Possible involvement of CCT5, RGS3, and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers. Ooe, A., Kato, K., Noguchi, S. Breast Cancer Res. Treat. (2007) [Pubmed]
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