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Gene Review

GPATCH8  -  G patch domain containing 8

Homo sapiens

Synonyms: G patch domain-containing protein 8, GPATC8, KIAA0553
 
 
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High impact information on GPATCH8

  • Sequencing the region surrounding the human alphaIIb locus showed the Granulin gene approximately 18 kb downstream to alphaIIb, and the KIAA0553 gene approximately 5.7 kb upstream [1].
  • RESULTS: Hypothetical protein KIAA0553 was expressed 120 times among 917 ESTs from an adult cardiac library (13.1%) compared only once among 8075 ESTs from fetal cardiac libraries (P < 10(-114)), this was confirmed using Northern analysis [2].

References

  1. The human platelet alphaIIb gene is not closely linked to its integrin partner beta3. Thornton, M.A., Poncz, M., Korostishevsky, M., Yakobson, E., Usher, S., Seligsohn, U., Peretz, H. Blood (1999) [Pubmed]
  2. Venn analysis as part of a bioinformatic approach to prioritize expressed sequence tags from cardiac libraries. McKinney, J.L., Murdoch, D.J., Wang, J., Robinson, J., Biltcliffe, C., Khan, H.M., Walker, P.M., Savage, J., Skerjanc, I., Hegele, R.A. Clin. Biochem. (2004) [Pubmed]
 
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