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Gene Review

Slitrk6  -  SLIT and NTRK-like family, member 6

Mus musculus

Synonyms: 4832410J21Rik, SLIT and NTRK-like protein 6, Sltk6
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High impact information on Slitrk6

  • Slitrk6 is a member of the Slitrk family of proteins, which are integral membrane proteins possessing two leucine-rich repeat (LRR) domains and a carboxy-terminal domain partially similar to that in the trk neurotrophin receptor proteins [1].
  • The expression compartment in the thalamus in which Slitrk6 was expressed was closely related to the Gbx2-expressing prosomere 2 [1].
  • Interestingly, the Slitrk6 expression in the CNS, cochlea, tongue, tooth primordial, and other organs was partially complementary to the expression of Nlrr3, which belongs to another family of neuronal LRR-containing transmembrane proteins [1].

Other interactions of Slitrk6

  • Here, I show that Slitrk6 is uniquely expressed in various organs, different from other Slitrk genes which are predominantly expressed in neural tissues [1].


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