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Gene Review

Pde5a  -  phosphodiesterase 5A, cGMP-specific

Mus musculus

Synonyms: CGB-PDE, Cgbpde, Cn5n, PDE5A1, Pde5, ...
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High impact information on Pde5a

  • In addition, caspase-3 induced an approximately 80% reduction in the activity of a partially purified preparation of PDE5A1 in the presence of rod PDEgamma [1].
  • In contrast with both PDE6 and PDE5A1, rod PDEgamma was without effect on this enzyme [1].

Other interactions of Pde5a

  • We have investigated whether the proteolysis of members of the cGMP binding phosphodiesterases (PDE6, PDE5A1, and PDE10A2) by caspase-3 is modulated by the gamma inhibitor subunit of PDE6 [1].


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