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Gene Review

RT1-E  -  RT1 class I, locus E

Rattus norvegicus

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High impact information on RT1-E

  • A cDNA clone encoding a RT1 E beta chain was isolated from a cDNA library prepared from Wistar (RT1 mu) spleen poly(A) RNA by screening with DNA fragments encoding a RT1 A beta chain [1].
  • The nucleotide sequence of this cDNA insert was determined and was shown to encode a complete RT1 E beta chain [1].
  • We conclude that recognition of an allogeneic MHC class Ib RT1-E molecule activates NK cells and the specific cytolytic response could be regarded as adaptive [2].

References

 
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