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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Wnt3  -  wingless-type MMTV integration site family...

Rattus norvegicus

 
 
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Disease relevance of Wnt3_predicted

  • In ADX rats injected with 1 x 10(6) cells, disease onset was comparable to INT 4 x 10(7) rats but disease progression was equally rapid and T-cell apoptosis (1.4-8.5%) was similarly low to that seen in ADX rats given the higher dose of cells [1].
 

High impact information on Wnt3_predicted

  • Wnt3 was expressed at low levels in both PC12 and PC12/flat, but was absent in PC12/Wnt1 cells [2].

References

  1. Apoptosis of T cells and macrophages in the central nervous system of intact and adrenalectomized Lewis rats during experimental allergic encephalomyelitis. Smith, T., Schmied, M., Hewson, A.K., Lassmann, H., Cuzner, M.L. J. Autoimmun. (1996) [Pubmed]
  2. Differential expression of Wnt genes in normal and flat variants of PC12 cells, a cell line responsive to ectopic Wnt1 expression. Erdreich-Epstein, A., Shackleford, G.M. Growth Factors (1998) [Pubmed]
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