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Gene Review

Fmr1  -  fragile X mental retardation 1

Rattus norvegicus

Synonyms: FMRP, Fragile X mental retardation protein 1 homolog, Protein FMR-1
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High impact information on Fmr1

  • In contrast to its dendritic localization, mGluR activation diminished FMRP, but not Fmr1 mRNA, localization at synapses [1].
  • We investigated whether neuronal activity and glutamatergic signals regulate trafficking of FMRP and its encoding Fmr1 mRNA into dendrites or at synapses [1].


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