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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Hk3  -  hexokinase 3 (white cell)

Rattus norvegicus

Synonyms: HK III, Hexokinase type III, Hexokinase-3
 
 
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Disease relevance of Hk3

  • Although the isozyme pattern generally resembled that of fetal liver or hepatoma cells, the relatively high activity of hexokinase Type III in CCl(4) treatment characterizes the pattern of hexokinase isozyme in acue liver damage [1].
 

High impact information on Hk3

  • This same derivative was readily able to bind hepatic glucokinase and hexokinase type III, but Sepharose-N-amino-octanoyl-glucosamine was better for these enzymes and was the only derivative capable of binding kidney hexokinase type I efficiently [2].

References

  1. Hexokinase isozyme pattern in CCl(4)-injured rat liver. Ueda, M., Taketa, K., Kosaka, K. Clin. Chim. Acta (1975) [Pubmed]
  2. Purification of the hexokinases by affinity chromatography on sepharose-N-aminoacylglucosamine derivates. Design of affinity matrices from free solution kinetics. Wright, C.L., Warsy, A.S., Holroyde, M.J., Trayer, I.P. Biochem. J. (1978) [Pubmed]
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