Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

X11L - CG5675 gene product from transcript CG5675-RF

Drosophila melanogaster

Synonyms: CG5675, CG5678, Dmel\CG5675, Dmint, Dmint1, ...

Vishnu, S. et al., Hase, M. et al.

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High impact information on X11L

X11/Mint family members in C. elegans (LIN-10) and vertebrates are believed to function as adaptor proteins and to regulate the assembly of multi-subunit complexes at the synapse, thereby linking the vesicle cycle to cell adhesion [1].
Overexpression of dX11L on post-mitotic neurons had a lethal effect on flies and, when it was localized to the eye imaginal disc, disruption of compound eye morphology due to enhanced apoptosis of neuronal cells was observed [2].

References

The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Vishnu, S., Hertenstein, A., Betschinger, J., Knoblich, J.A., Gert de Couet, H., Fischbach, K.F. Dev. Biol. (2006) [Pubmed]
Expression and characterization of the Drosophila X11-like/Mint protein during neural development. Hase, M., Yagi, Y., Taru, H., Tomita, S., Sumioka, A., Hori, K., Miyamoto, K., Sasamura, T., Nakamura, M., Matsuno, K., Suzuki, T. J. Neurochem. (2002) [Pubmed]

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