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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

pop2  -  F-box/WD repeat protein Pop2

Schizosaccharomyces pombe 972h-

 
 
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High impact information on SPAC4D7.03

  • We show here that, despite their structural and functional similarities, the pop1 and pop2 genes fail to complement each other's deletion phenotypes, indicating that they perform non-redundant, but potentially interdependent, functions in proteolysis [1].
  • RESULTS: We have cloned and characterized the pop2+ gene which encodes the Pop1-related F-box/WD-repeat protein [2].

References

  1. F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p. Wolf, D.A., McKeon, F., Jackson, P.K. Curr. Biol. (1999) [Pubmed]
  2. Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase. Kominami, K., Ochotorena, I., Toda, T. Genes Cells (1998) [Pubmed]
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