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Gene Review:

cadX - CadX

Staphylococcus aureus

Massidda, O. et al.

Massidda, Mingoia, Fadda, Whalen, Montanari, Varaldo,

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High impact information on cadX

The well-established S. aureus laboratory strain ATCC 29213 was also found to express cadD-cadX-mediated cadmium resistance. pBORa53 could be re-isolated from transformants obtained by transferring it into a PRP-susceptible recipient [1].

Biological context of cadX

From a collection of 30 S. aureus isolates with borderline PRP MIC levels, 27 matched strain a53 in the positive amplification reactions with all of the four primer pairs targeting the cadD-cadX region, the presence of the 17.3-kb plasmid, and the level of cadmium resistance [1].
Among the other 11 ORFs identified, two were homologous to cadmium resistance determinants of Staphylococcus lugdunensis and to the cadD and cadX genes recently detected in S. aureus [1].

References

Analysis of the beta-lactamase plasmid of borderline methicillin-susceptible Staphylococcus aureus: focus on bla complex genes and cadmium resistance determinants cadD and cadX. Massidda, O., Mingoia, M., Fadda, D., Whalen, M.B., Montanari, M.P., Varaldo, P.E. Plasmid (2006) [Pubmed]

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