The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

FBXW2  -  F-box and WD repeat domain containing 2

Homo sapiens

Synonyms: F-box and WD-40 domain-containing protein 2, F-box/WD repeat-containing protein 2, FBW2, FWD2, Fwd2, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on FBXW2

  • We show that hFBW2 interacts with hGCMa in a phosphorylation-dependent manner and promotes hGCMa ubiquitination [1].
  • The SDS-H3 CH(2) protons were resolved from the bulk of the SDS protons, with peaks and shoulders at 1.25 ppm, which indicated an especially strong interaction of the SDS hydrophobic tail with MD6 and some less intense interactions with MD2, 4, and 5 [2].


  1. FBW2 targets GCMa to the ubiquitin-proteasome degradation system. Yang, C.S., Yu, C., Chuang, H.C., Chang, C.W., Chang, G.D., Yao, T.P., Chen, H. J. Biol. Chem. (2005) [Pubmed]
  2. Two-dimensional rotating-frame Overhauser spectroscopy (ROESY) and (13)C NMR study of the interactions between maltodextrin and an anionic surfactant. Wangsakan, A., McClements, D.J., Chinachoti, P., Charles Dickinson, L. Carbohydr. Res. (2004) [Pubmed]
WikiGenes - Universities