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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

FBXW2  -  F-box and WD repeat domain containing 2

Homo sapiens

Synonyms: F-box and WD-40 domain-containing protein 2, F-box/WD repeat-containing protein 2, FBW2, FWD2, Fwd2, ...
 
 
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High impact information on FBXW2

  • We show that hFBW2 interacts with hGCMa in a phosphorylation-dependent manner and promotes hGCMa ubiquitination [1].
  • The SDS-H3 CH(2) protons were resolved from the bulk of the SDS protons, with peaks and shoulders at 1.25 ppm, which indicated an especially strong interaction of the SDS hydrophobic tail with MD6 and some less intense interactions with MD2, 4, and 5 [2].

References

  1. FBW2 targets GCMa to the ubiquitin-proteasome degradation system. Yang, C.S., Yu, C., Chuang, H.C., Chang, C.W., Chang, G.D., Yao, T.P., Chen, H. J. Biol. Chem. (2005) [Pubmed]
  2. Two-dimensional rotating-frame Overhauser spectroscopy (ROESY) and (13)C NMR study of the interactions between maltodextrin and an anionic surfactant. Wangsakan, A., McClements, D.J., Chinachoti, P., Charles Dickinson, L. Carbohydr. Res. (2004) [Pubmed]
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