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Gene Review

Svet1  -  subventricular expressed transcript 1

Mus musculus

 
 
 
 
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High impact information on Svet1

  • Interestingly, in the Pax6/small eye mutant, Svet1 activity was abolished in the SVZ and in the upper part of the cortical plate while the Otx1 expression domain remained unchanged [1].
  • Therefore, using Svet1 and Otx1 as cell-type-specific molecular markers for the upper and deep cortical layers we conclude that the Sey mutation affects predominantly the differentiation of the SVZ cells that fail to migrate into the cortical plate [1].
  • Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression [1].
 

Other interactions of Svet1

  • Later in development, Svet1 and Otx1 were expressed in subsets of cells of upper (II-IV) and deep (V-VI) layers, respectively [1].

References

  1. Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression. Tarabykin, V., Stoykova, A., Usman, N., Gruss, P. Development (2001) [Pubmed]
 
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