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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ak3  -  adenylate kinase 3

Rattus norvegicus

Synonyms: AK 3, Adenylate kinase 3, Adenylate kinase 3 alpha-like 1, Ak3l1, Akl3l, ...
 
 
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High impact information on Ak3

  • Changes in the levels of three adenylate kinase isozymes (AK1, AK2, and AK3) in the rat brain during development were investigated by immunoblot analysis [1].
  • AK3 mRNA was detected in most tissues examined, suggesting that AK3 gene expression is constitutive [2].
 

Anatomical context of Ak3

 

Other interactions of Ak3

  • The levels of AK1 and AK3 of the whole brain increased after birth, while AK2 was detected only in the early embryonic period [1].
 

Analytical, diagnostic and therapeutic context of Ak3

  • We isolated cDNAs for rat AK isozymes (AK1, AK2, and AK3), determined their mRNAs in rat tissues by Northern blot analysis, and measured the isozyme activities [2].

References

  1. Distribution and developmental changes of adenylate kinase isozymes in the rat brain: localization of adenylate kinase 1 in the olfactory bulb. Inouye, S., Yamada, Y., Miura, K., Suzuki, H., Kawata, K., Shinoda, K., Nakazawa, A. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  2. Tissue-specific and developmentally regulated expression of the genes encoding adenylate kinase isozymes. Tanabe, T., Yamada, M., Noma, T., Kajii, T., Nakazawa, A. J. Biochem. (1993) [Pubmed]
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