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Gene Review:

UL22 - type 1 membrane protein; contains a signal...

Human herpesvirus 1

Khattar, S.K. et al., Nunberg, J.H. et al.

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Disease relevance of UL22

The location of the TK gene and the location and orientation of flanking FHV genes, homologs of herpes simplex virus type 1 UL24 and UL22, are conserved among alphaherpesviruses [1].
Sera against UL22 protein immunoprecipitated a protein of 108 kDa from BHV-1-infected MDBK cells and purified virions, which was modified only by N-linked oligosaccharides and was named glycoprotein gH [2].

References

Identification of the thymidine kinase gene of feline herpesvirus: use of degenerate oligonucleotides in the polymerase chain reaction to isolate herpesvirus gene homologs. Nunberg, J.H., Wright, D.K., Cole, G.E., Petrovskis, E.A., Post, L.E., Compton, T., Gilbert, J.H. J. Virol. (1989) [Pubmed]
Identification and characterization of a bovine herpesvirus-1 (BHV-1) glycoprotein gL which is required for proper antigenicity, processing, and transport of BHV-1 glycoprotein gH. Khattar, S.K., van Drunen Littel-van den Harke, S., Attah-Poku, S.K., Babiuk, L.A., Tikoo, S.K. Virology (1996) [Pubmed]

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