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Gene Review

STK36  -  serine/threonine kinase 36

Homo sapiens

Synonyms: FU, Fused homolog, KIAA1278, Serine/threonine-protein kinase 36
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Disease relevance of STK36

  • The human developmental disorder Syndactyly type 1 (SD1) maps to this region on chromosome 2 and the FU coding region was sequenced using genomic DNA from an affected individual in a linked family [1].
  • When the concentration of (FU)RNA/RNA was above approximately 200 ng/mg, FU was effectual in unresectable carcinomas [2].

High impact information on STK36


  1. The FU gene and its possible protein isoforms. Østerlund, T., Everman, D.B., Betz, R.C., Mosca, M., Nöthen, M.M., Schwartz, C.E., Zaphiropoulos, P.G., Toftgård, R. BMC Genomics (2004) [Pubmed]
  2. Preliminary evidence that incorporation of 5-fluorouracil into RNA correlates with antitumor response. Matsuoka, H., Ueo, H., Sugimachi, K., Akiyoshi, T. Cancer Invest. (1992) [Pubmed]
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