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Gene Review

SALL3  -  spalt-like transcription factor 3

Homo sapiens

Synonyms: Sal-like protein 3, ZNF796, Zinc finger protein 796, Zinc finger protein SALL3, hSALL3
 
 
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High impact information on SALL3

  • The T-DMR sequence is also conserved in the human genome at the SALL3 locus of chromosome 18q23, which has been suggested to be involved in the 18q deletion syndrome [1].
  • The chromosomal localization of SALL3 at 18q23 suggests that haploinsufficiency of this gene might contribute to the phenotype of patients with 18q deletion syndrome [2].

References

  1. The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice. Ohgane, J., Wakayama, T., Senda, S., Yamazaki, Y., Inoue, K., Ogura, A., Marh, J., Tanaka, S., Yanagimachi, R., Shiota, K. Genes Cells (2004) [Pubmed]
  2. SALL3, a new member of the human spalt-like gene family, maps to 18q23. Kohlhase, J., Hausmann, S., Stojmenovic, G., Dixkens, C., Bink, K., Schulz-Schaeffer, W., Altmann, M., Engel, W. Genomics (1999) [Pubmed]
 
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