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Gene Review

gltA  -  citrate synthase

Wolbachia endosymbiont of Drosophila melanogaster

 
 
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Disease relevance of gltA

  • Intragenic recombination affects gltA, with a clear evidence of horizontal DNA transfers within and between divergent Wolbachia supergroups [1].
  • Its position in the phylogenetic tree constructed with gltA confirmed that found in a phylogenetic tree constructed with 16S rRNA genes and that it belongs in the alpha subgroup of the class Proteobacteria and that it is closely related to but independent from the genera Ehrlichia, Anaplasma, and Neorickettsia [2].

References

  1. Widespread recombination throughout Wolbachia genomes. Baldo, L., Bordenstein, S., Wernegreen, J.J., Werren, J.H. Mol. Biol. Evol. (2006) [Pubmed]
  2. Culture and phenotypic characterization of a Wolbachia pipientis isolate. Fenollar, F., La Scola, B., Inokuma, H., Dumler, J.S., Taylor, M.J., Raoult, D. J. Clin. Microbiol. (2003) [Pubmed]
 
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