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Gene Review

GMFA  -  glia maturation factor, alpha

Homo sapiens

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Disease relevance of GMFA

  • We demonstrate clearly that GMFA is able to ablate ovomucoid-induced allergic reactions in sensitized mice [1].
  • This paper describes an independent evaluation of a peer-led STD/HIV prevention intervention conducted by Gay Men Fighting AIDS (GMFA) in a public sex environment (PSE) [2].

High impact information on GMFA

  • Abrogation of the allergic response with complete suppression of anaphylactic symptoms and lower serum histamine levels was observed in the desensitized group by GMFA, accompanied by significantly reduced ovomucoid-specific IgE and IgG1 levels and enhanced specific IgG and IgG2a levels [1].

Analytical, diagnostic and therapeutic context of GMFA

  • The EEG was recorded simultaneously with 60 scalp electrodes (41 electrodes were used for analysis); the TMS-evoked activation was estimated by the area under the global mean field amplitude (GMFA) time curve [3].
  • Data collected showed that condoms provided by GMFA, as well as from other sources, were being used in the PSE [2].


  1. Ablation of ovomucoid-induced allergic response by desensitization with recombinant ovomucoid third domain in a murine model. Rupa, P., Mine, Y. Clin. Exp. Immunol. (2006) [Pubmed]
  2. An evaluation of peer-led STD/HIV prevention work in a public sex environment. French, R., Power, R., Mitchell, S. AIDS care. (2000) [Pubmed]
  3. Alcohol reduces prefrontal cortical excitability in humans: a combined TMS and EEG study. Kähkönen, S., Wilenius, J., Nikulin, V.V., Ollikainen, M., Ilmoniemi, R.J. Neuropsychopharmacology (2003) [Pubmed]
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