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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SLC36A3  -  solute carrier family 36, member 3

Homo sapiens

Synonyms: PAT3, Proton-coupled amino acid transporter 3, Proton/amino acid transporter 3, Solute carrier family 36 member 3, TRAMD2, ...
 
 
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High impact information on SLC36A3

  • These two proteins share a region of homology with talin and members of the FERM superfamily of proteins.We have determined that a functional UNC-112::GFP fusion protein colocalizes with PAT-3/beta-integrin in both adult and embryonic body wall muscle [1].
  • The mouse PAT3 mRNA is expressed in testis of adult mice [2].
  • The Pat subspecies was grouped into Pat1-Pat3, based on restriction fragment length polymorphism (RFLP) and ribosomal DNA (rDNA) internal transcribed spacer (ITS) sequences in previous studies [3].
  • Prespecified pattern 1 was identified in 81%, PAT 2 in 8%, and PAT 3 in 11% of the patients [4].
 

Anatomical context of SLC36A3

References

  1. The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane. Rogalski, T.M., Mullen, G.P., Gilbert, M.M., Williams, B.D., Moerman, D.G. J. Cell Biol. (2000) [Pubmed]
  2. A cluster of proton/amino acid transporter genes in the human and mouse genomes. Boll, M., Foltz, M., Rubio-Aliaga, I., Daniel, H. Genomics (2003) [Pubmed]
  3. Sequence diversity of mating-type genes in Phaeosphaeria avenaria. Ueng, P.P., Dai, Q., Cui, K.R., Czembor, P.C., Cunfer, B.M., Tsang, H., Arseniuk, E., Bergstrom, G.C. Curr. Genet. (2003) [Pubmed]
  4. Basic components and patterns of acute ischemia recovery assessed from continuous ST monitoring in acute myocardial infarction treated by thrombolytic therapy. Col, J., Pirenne, B., Decoster, O., Payen, B., Deligne, B., Purnode, P., Renkin, J. Journal of electrocardiology. (1994) [Pubmed]
  5. Organization and expression of the SLC36 cluster of amino acid transporter genes. Bermingham, J.R., Pennington, J. Mamm. Genome (2004) [Pubmed]
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