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Gene Review:

hilA - invasion protein regulator

Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67

This record was discontinued.

Lichtensteiger, C.A. et al.

Lichtensteiger, Vimr,

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Disease relevance of hilA

The role of hilA may be conserved across Salmonella serovars and host species [1].
Our data support that hilA in S. choleraesuis infections of pigs has a role in enteric but not systemic infections similar to that of S. typhimurium in the murine model of human typhoid fever [1].

High impact information on hilA

In the broad host range serovar S. typhimurium, hilA regulates invasion genes in the first pathogenicity island and is required for enteric but not systemic infections in mice experimentally infected with S. typhimurium [1].

References

Systemic and enteric colonization of pigs by a hilA signature-tagged mutant of Salmonella choleraesuis. Lichtensteiger, C.A., Vimr, E.R. Microb. Pathog. (2003) [Pubmed]

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