Gene Review:
nkx3.2 - NK3 homeobox 2
Danio rerio
Synonyms:
SO:0000704
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High impact information on bapx1
- In hand2 mutants, bapx1 expression is present at the joint region, and expanded ventrally [1].
- Next we show that along the DV axis of the early first arch primordia, bapx1 is expressed in an intermediate domain, which later marks the jaw joint, and this expression requires edn1 function. bapx1 function is required for formation of the jaw joint, the joint-associated retroarticular process of Meckel's cartilage, and the retroarticular bone [1].
References
- Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint. Miller, C.T., Yelon, D., Stainier, D.Y., Kimmel, C.B. Development (2003) [Pubmed]
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