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Gene Review: 

vanA  -  vanillate O-demethylase, oxygenase subunit

Pseudomonas protegens Pf-5

 
 
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Disease relevance of vanA

 

High impact information on vanA

  • The genomic region of BF13-97 flanking the transposon's site of insertion was cloned and sequenced revealing two open reading frames of 1,062 (vanA) and 954 (vanB) bp, respectively [1].
 

Chemical compound and disease context of vanA

  • These genes were localized downstream of the eugenol catabolism genes vanA and vanB, encoding vanillate-O-demethylase, on an EcoRI fragment (E230) that has recently been cloned from a Pseudomonas sp. strain HR199 genomic library [2].

References

  1. Bioconversion of ferulic acid into vanillic acid by means of a vanillate-negative mutant of Pseudomonas fluorescens strain BF13. Civolani, C., Barghini, P., Roncetti, A.R., Ruzzi, M., Schiesser, A. Appl. Environ. Microbiol. (2000) [Pubmed]
  2. Identification and molecular characterization of the eugenol hydroxylase genes (ehyA/ehyB) of Pseudomonas sp. strain HR199. Priefert, H., Overhage, J., Steinbüchel, A. Arch. Microbiol. (1999) [Pubmed]
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