The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

LRRTM3  -  leucine rich repeat transmembrane neuronal 3

Homo sapiens

Synonyms: Leucine-rich repeat transmembrane neuronal protein 3, UNQ803/PRO1693
 
 
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Psychiatry related information on LRRTM3

 

High impact information on LRRTM3

  • Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both LOAD and elevated plasma Abeta42, and is structurally similar to a family of neuronal receptors that includes the NOGO receptor, an inhibitor of neuronal regeneration and APP processing [1].
  • LRRTM3 is expressed nearly exclusively in the nervous system, including regions affected during AD, such as the dentate gyrus [1].

References

  1. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease. Majercak, J., Ray, W.J., Espeseth, A., Simon, A., Shi, X.P., Wolffe, C., Getty, K., Marine, S., Stec, E., Ferrer, M., Strulovici, B., Bartz, S., Gates, A., Xu, M., Huang, Q., Ma, L., Shughrue, P., Burchard, J., Colussi, D., Pietrak, B., Kahana, J., Beher, D., Rosahl, T., Shearman, M., Hazuda, D., Sachs, A.B., Koblan, K.S., Seabrook, G.R., Stone, D.J. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities