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SLC35B2  -  solute carrier family 35 (adenosine 3'...

Homo sapiens

Synonyms: Adenosine 3'-phospho 5'-phosphosulfate transporter 1, PAPS transporter 1, PAPST1, PSEC0149, SLL, ...
 
 
 
 
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High impact information on SLC35B2

  • The amino acid sequence of PAPST1 (432 amino acids) exhibited 48.1% identity with SLL (465 amino acids), and hydropathy analysis predicted the two to be type III transmembrane proteins [1].
  • In human tissues, PAPST1 is highly expressed in the placenta and pancreas and present at lower levels in the colon and heart [1].
  • An RNA interference fly of sll produced with a GAL4-UAS system revealed that the PAPS transporter is essential for viability [1].

References

  1. Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter. Kamiyama, S., Suda, T., Ueda, R., Suzuki, M., Okubo, R., Kikuchi, N., Chiba, Y., Goto, S., Toyoda, H., Saigo, K., Watanabe, M., Narimatsu, H., Jigami, Y., Nishihara, S. J. Biol. Chem. (2003) [Pubmed]
 
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