The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

NME9  -  NME/NM23 family member 9

Homo sapiens

Synonyms: NM23-H9, TXL-2, TXL2, TXNDC6, Thioredoxin domain-containing protein 6, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on TXNDC6

  • Using in vitro translated proteins, we demonstrate that full-length Txl-2 weakly associates with microtubules [1].
  • By quantitative real time PCR we demonstrate that Txl-2 mRNA is ubiquitously expressed, with testis and lung having the highest levels of expression [1].
  • The Txl-2 gene spans approximately 28 kb, is organized into 11 exons, and maps at locus 3q22.3-q23 [1].
  • The Txl-2 open reading frame codes for a protein of 330 amino acids consisting of two distinct domains: an N-terminal domain typical of thioredoxins and a C-terminal domain belonging to the nucleoside-diphosphate kinase family, separated by a small interface domain [1].


  1. Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme. Sadek, C.M., Jiménez, A., Damdimopoulos, A.E., Kieselbach, T., Nord, M., Gustafsson, J.A., Spyrou, G., Davis, E.C., Oko, R., van der Hoorn, F.A., Miranda-Vizuete, A. J. Biol. Chem. (2003) [Pubmed]
WikiGenes - Universities