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Gene Review

Socs36E  -  Suppressor of cytokine signaling at 36E

Drosophila melanogaster

Synonyms: CG15154, Dmel\CG15154, SOCS, SOCS36E, SocS36E, ...
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High impact information on Socs36E

  • Socs36E is expressed zygotically, predominantly during embryogenesis, in a highly dynamic pattern [1].
  • In vivo expression of SOCS36E in transgenic flies results in several adult phenotypes [1].
  • Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway [2].
  • Examination of one Drosophila SOCS homologue, Socs36E, demonstrated that its expression is responsive to JAK pathway activity and it is capable of downregulating JAK signaling, similar to the well characterized mammalian SOCS [3].


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