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Gene Review

CYCSP52  -  cytochrome c, somatic pseudogene 52

Homo sapiens

Synonyms: HC6, HCP2
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High impact information on CYCSP52

  • We isolated a human homolog of C. elegans HCP6, a protein distantly related to the condensin subunit hCAP-D2, and we named this homolog hHCP-6 [1].
  • Interestingly, other hydroxamates with different chain length were not nearly as effective as HC6 in inducing neuroblastoma cell differentiation [2].


  1. Identification of a subunit of a novel Kleisin-beta/SMC complex as a potential substrate of protein phosphatase 2A. Yeong, F.M., Hombauer, H., Wendt, K.S., Hirota, T., Mudrak, I., Mechtler, K., Loregger, T., Marchler-Bauer, A., Tanaka, K., Peters, J.M., Ogris, E. Curr. Biol. (2003) [Pubmed]
  2. Aminohexanoic hydroxamate is a potent inducer of the differentiation of mouse neuroblastoma cells. Lu, J., Chen, Z.P., Yan, Y.P., Knapp, S., Schugar, H., Chen, K.Y. Cancer Lett. (2000) [Pubmed]
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