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Gene Review

Lmo2  -  LIM domain only 2

Rattus norvegicus

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Disease relevance of Lmo2

  • The developmental expression pattern of SRF overlaps significantly with that of myotonic dystrophy protein kinase, a potential upstream regulator, and of the LIM-only genes Lmo1, Lmo2 and Lmo3, whose products belong to a family of proteins known to be strong positive regulators of SRF's transcriptional activity [1].


  1. Developmental expression of serum response factor in the rat central nervous system. Stringer, J.L., Belaguli, N.S., Iyer, D., Schwartz, R.J., Balasubramanyam, A. Brain Res. Dev. Brain Res. (2002) [Pubmed]
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