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Gene Review:

Hsc70-5 - Heat shock protein cognate 5

Drosophila melanogaster

Synonyms: CG8542, Dmel\CG8542, HSC-70, HSC5, HSC70, ...

Gerrard, B. et al., Rubin, D.M. et al.

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High impact information on Hsc70-5

We report the identification of two new members of the Drosophila melanogaster HSP70 gene family, HSC3 and HSC5 [1].
The gene is adjacent to Hsc5, a locus mapped to chromosome 2, band 50, and is named Mdr50 [2].

Analytical, diagnostic and therapeutic context of Hsc70-5

Sequence analysis predicts that HSC5 encodes a 74-kDa protein with a characteristic mitochondrial leader sequence [1].

References

Genomic structure and sequence analysis of Drosophila melanogaster HSC70 genes. Rubin, D.M., Mehta, A.D., Zhu, J., Shoham, S., Chen, X., Wells, Q.R., Palter, K.B. Gene (1993) [Pubmed]
Analysis of Mdr50: a Drosophila P-glycoprotein/multidrug resistance gene homolog. Gerrard, B., Stewart, C., Dean, M. Genomics (1993) [Pubmed]

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