Gene Review:
HSPA9 - heat shock 70kDa protein 9 (mortalin)
Homo sapiens
Synonyms:
75 kDa glucose-regulated protein, CRP40, CSA, GRP-75, GRP75, ...
- Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31. Xie, H., Hu, Z., Chyna, B., Horrigan, S.K., Westbrook, C.A. Leukemia (2000)
- Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival. Dundas, S.R., Lawrie, L.C., Rooney, P.H., Murray, G.I. J. Pathol. (2005)
- Expression of mortalin in patients with chronic atrial fibrillation. Kirmanoglou, K., Hannekum, A., Schäfler, A.E. Basic Res. Cardiol. (2004)
- Lateral sleeping position reduces severity of central sleep apnea / Cheyne-Stokes respiration. Szollosi, I., Roebuck, T., Thompson, B., Naughton, M.T. Sleep. (2006)
- Mechanism of inhibition of granulopoiesis by ethanol. Imperia, P.S., Chikkappa, G., Phillips, P.G. Proc. Soc. Exp. Biol. Med. (1984)
- Comparisons of four methods of estimating physical activity in adult women. Leenders NYJM, n.u.l.l., Sherman, W.M., Nagaraja, H.N. Medicine and science in sports and exercise. (2000)
- Effects of moment of inertia on simple reaction time. Anson, J.G. Journal of motor behavior. (1989)
- Management of severe neutropenia with cyclosporin during initial treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis. Imashuku, S., Hibi, S., Kuriyama, K., Tabata, Y., Hashida, T., Iwai, A., Kato, M., Yamashita, N., Oda MUchida, M., Kinugawa, N., Sawada, M., Konno, M. Leuk. Lymphoma (2000)
- The glycosaminoglycans of the human artery and their changes in atherosclerosis. Stevens, R.L., Colombo, M., Gonzales, J.J., Hollander, W., Schmid, K. J. Clin. Invest. (1976)
- Use of bone-marrow culture in prediction of acute leukaemic transformation in preleukaemia. Francis, G.E., Wing, M.A., Miller, E.J., Berney, J.J., Wonke, B., Hoffbrand, A.V. Lancet (1983)
- Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. Szabadkai, G., Bianchi, K., V??rnai, P., De Stefani, D., Wieckowski, M.R., Cavagna, D., Nagy, A.I., Balla, T., Rizzuto, R. J. Cell Biol. (2006)
- Mitoxantrone, etoposide, and cyclosporine therapy in pediatric patients with recurrent or refractory acute myeloid leukemia. Dahl, G.V., Lacayo, N.J., Brophy, N., Dunussi-Joannopoulos, K., Weinstein, H.J., Chang, M., Sikic, B.I., Arceci, R.J. J. Clin. Oncol. (2000)
- Effect of cyclosporin and interleukin-2 on the restoration of in vitro immune responses to cytomegalovirus. Converse, P.J., Hess, A.D. Scand. J. Immunol. (1985)
- In vivo and in vitro effects of lithium on granulopoiesis in human neutropenic disorders. Robinson, W.A., Entringer, M.A., Huber, J., Gupta, R. Adv. Exp. Med. Biol. (1980)
- Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts. Kaul, S.C., Yaguchi, T., Taira, K., Reddel, R.R., Wadhwa, R. Exp. Cell Res. (2003)
- Mortalin-MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation. Wadhwa, R., Yaguchi, T., Hasan, M.K., Taira, K., Kaul, S.C. Biochem. Biophys. Res. Commun. (2003)
- Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60. Wadhwa, R., Takano, S., Kaur, K., Aida, S., Yaguchi, T., Kaul, Z., Hirano, T., Taira, K., Kaul, S.C. Biochem. J. (2005)
- Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2. Kaula, S.C., Reddelb, R.R., Sugiharac, T., Mitsuia, Y., Wadhwac, R. FEBS Lett. (2000)
- Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74. Schwarzer, C., Barnikol-Watanabe, S., Thinnes, F.P., Hilschmann, N. Int. J. Biochem. Cell Biol. (2002)
- Cloning and subcellular localization of human mitochondrial hsp70. Bhattacharyya, T., Karnezis, A.N., Murphy, S.P., Hoang, T., Freeman, B.C., Phillips, B., Morimoto, R.I. J. Biol. Chem. (1995)
- Implication of PBP74/mortalin/GRP75 in the radio-adaptive response. Carette, J., Lehnert, S., Chow, T.Y. Int. J. Radiat. Biol. (2002)
- Loss of Hspa9b in zebrafish recapitulates the ineffective hematopoiesis of the myelodysplastic syndrome. Craven, S.E., French, D., Ye, W., de Sauvage, F., Rosenthal, A. Blood (2005)
- Lipid transfer protein I facilitated transfer of cyclosporine from low- to high-density lipoproteins is only partially dependent on its cholesteryl ester transfer activity. Wasan, K.M., Ramaswamy, M., Wong, W., Pritchard, P.H. J. Pharmacol. Exp. Ther. (1998)
- Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway. Widodo, N., Deocaris, C.C., Kaur, K., Hasan, K., Yaguchi, T., Yamasaki, K., Sugihara, T., Ishii, T., Wadhwa, R., Kaul, S.C. J. Gerontol. A Biol. Sci. Med. Sci. (2007)
- Mercuric chloride-induced alterations in stress protein distribution in rat kidney. Stacchiotti, A., Lavazza, A., Rezzani, R., Borsani, E., Rodella, L., Bianchi, R. Histol. Histopathol. (2004)
- Mortalin controls centrosome duplication via modulating centrosomal localization of p53. Ma, Z., Izumi, H., Kanai, M., Kabuyama, Y., Ahn, N.G., Fukasawa, K. Oncogene (2006)
- Glucose regulated proteins 78 and 75 bind to the receptor for hyaluronan mediated motility in interphase microtubules. Kuwabara, H., Yoneda, M., Hayasaki, H., Nakamura, T., Mori, H. Biochem. Biophys. Res. Commun. (2006)
- Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin. Mizukoshi, E., Suzuki, M., Loupatov, A., Uruno, T., Hayashi, H., Misono, T., Kaul, S.C., Wadhwa, R., Imamura, T. Biochem. J. (1999)
- Structural and functional differences between mouse mot-1 and mot-2 proteins that differ in two amino acids. Deocaris, C.C., Yamasaki, K., Kaul, S.C., Wadhwa, R. Ann. N. Y. Acad. Sci. (2006)
- Transplantation of human or rodent tumors into cyclosporine-treated mice: a feasible model for studies of tumor biology and chemotherapy. Fingert, H.J., Treiman, A., Pardee, A.B. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Variability of the 15N chemical shielding tensors in the B3 domain of protein g from 15N relaxation measurements at several fields. Implications for backbone order parameters. Hall, J.B., Fushman, D. J. Am. Chem. Soc. (2006)