Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

PLA2G2C - phospholipase A2, group IIC

Homo sapiens

This record was replaced with 391013.

Tischfield, J.A. et al., Spirio, L.N. et al.

Tischfield, Xia, Shih, Klisak, Chen, Engle, Siakotos, Winstead, Seilhamer, Allamand, Gyapay, Lusis,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of PLA2G2C

Among 67 additional unrelated AAPC subjects, a stop mutation in PLA2G2C did not correlate with an increased burden of adenomatous polyps [1].

High impact information on PLA2G2C

The Group IIA phospholipase gene (PLA2G2A) protein coding regions exhibit significant homology with recently described Group IIC (PLA2G2C) and Group V (PLA2GV) genes [2].
Unlike its rodent counterpart, human PLA2G2C appears to be a nonfunctional pseudogene [2].

References

Three secretory phospholipase A(2) genes that map to human chromosome 1P35-36 are not mutated in individuals with attenuated adenomatous polyposis coli. Spirio, L.N., Kutchera, W., Winstead, M.V., Pearson, B., Kaplan, C., Robertson, M., Lawrence, E., Burt, R.W., Tischfield, J.A., Leppert, M.F., Prescott, S.M., White, R. Cancer Res. (1996) [Pubmed]
Low-molecular-weight, calcium-dependent phospholipase A2 genes are linked and map to homologous chromosome regions in mouse and human. Tischfield, J.A., Xia, Y.R., Shih, D.M., Klisak, I., Chen, J., Engle, S.J., Siakotos, A.N., Winstead, M.V., Seilhamer, J.J., Allamand, V., Gyapay, G., Lusis, A.J. Genomics (1996) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.