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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Adenomatous Polyps

 
 
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Disease relevance of Adenomatous Polyps

 

Psychiatry related information on Adenomatous Polyps

 

High impact information on Adenomatous Polyps

 

Chemical compound and disease context of Adenomatous Polyps

 

Biological context of Adenomatous Polyps

 

Anatomical context of Adenomatous Polyps

 

Gene context of Adenomatous Polyps

  • The immunostaining studies revealed a significant correlation between high p27Kip1 protein expression and high cyclin D1 expression in the adenomatous polyps and in the subset of carcinomas that had only nuclear p27Kip1 expression [26].
  • Hypermethylation of the promoter of hMLH1, consequent loss of hMLH1 expression, and MSI are at the basis of approximately 25% of adenomatous polyps developed in subjects with a SFDR affected by colorectal cancer [27].
  • One hyperplastic and seven adenomatous polyps with villous architecture displayed foci of diffuse and intestinal-type carcinoma, respectively; in all of these cases, MUC1 expression and signs of gastric differentiation were observed in both the non-malignant and the carcinomatous component [28].
  • Immunohistochemical analysis showed that expression of both MSH2 and MSH6 proteins was lost in the cancer cells of the 2 mutation carriers but only MSH6 protein expression was lost in 2 adenomatous polyps [29].
  • Our results suggest chromosomal aberrations contribute early to the progression of adenomatous polyps after biallelic APC inactivation [30].
 

Analytical, diagnostic and therapeutic context of Adenomatous Polyps

References

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