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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

gtpbp1  -  GTP binding protein 1

Danio rerio

Synonyms: SO:0000704, cb858, wu:fb36e06, wu:fi39g05, zgc:66228
 
 
 
 
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Disease relevance of gtpbp1

  • Activation of either receptor led to a decline in the intracellular concentration of cGMP, a process that was inhibited in cells treated with pertussis toxin, reduced by suppression of the expression of the heterotrimeric GTP-binding protein (G protein) transducin, and suppressed through inhibition of cGMP-specific phosphodiesterase (PDE) activity [1].

References

  1. Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP. Ahumada, A., Slusarski, D.C., Liu, X., Moon, R.T., Malbon, C.C., Wang, H.Y. Science (2002) [Pubmed]
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