Gene Review:
Gtpbp1 - GTP binding protein 1
Mus musculus
Synonyms:
AL022987, AW045683, C85212, G-protein 1, GP-1, ...
- Microinjection of mRNA coding for an anti-Golgi antibody inhibits intracellular transport of a viral membrane protein. Burke, B., Warren, G. Cell (1984)
- The GTP-binding protein, Go, regulates neuronal calcium channels. Hescheler, J., Rosenthal, W., Trautwein, W., Schultz, G. Nature (1987)
- Regulation of the differentiation of teratocarcinoma cells into primitive endoderm by G alpha i2. Watkins, D.C., Johnson, G.L., Malbon, C.C. Science (1992)
- Vaccinia virus recombinants: expression of VSV genes and protective immunization of mice and cattle. Mackett, M., Yilma, T., Rose, J.K., Moss, B. Science (1985)
- The glycoprotein isolated from vesicular stomatitis virus is mitogenic for mouse B lymphocytes. Goodman-Snitkoff, G., Mannino, R.J., McSharry, J.J. J. Exp. Med. (1981)
- Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice. Hensler, J.G., Ladenheim, E.E., Lyons, W.E. J. Neurochem. (2003)
- Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients. Maxwell, C.R., Liang, Y., Kelly, M.P., Kanes, S.J., Abel, T., Siegel, S.J. Neuroscience (2006)
- Regulation of G protein-mediated adenylyl cyclase in striatum and cortex of opiate-dependent and opiate withdrawing mice. Kaplan, G.B., Sethi, R.K., McClelland, E.G., Leite-Morris, K.A. Brain Res. (1998)
- Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease. Lumbreras, M., Baamonde, C., Mart??nez-Cu??, C., Lubec, G., Cairns, N., Sall??s, J., Dierssen, M., Fl??rez, J. Amino Acids (2006)
- Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes. Kitanaka, J., Wang, X.B., Kitanaka, N., Hembree, C.M., Uhl, G.R. DNA Seq. (2001)
- Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Yalcin, B., Willis-Owen, S.A., Fullerton, J., Meesaq, A., Deacon, R.M., Rawlins, J.N., Copley, R.R., Morris, A.P., Flint, J., Mott, R. Nat. Genet. (2004)
- PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Patrucco, E., Notte, A., Barberis, L., Selvetella, G., Maffei, A., Brancaccio, M., Marengo, S., Russo, G., Azzolino, O., Rybalkin, S.D., Silengo, L., Altruda, F., Wetzker, R., Wymann, M.P., Lembo, G., Hirsch, E. Cell (2004)
- Spatiotemporal regulation of endothelin receptor-B by SOX10 in neural crest-derived enteric neuron precursors. Zhu, L., Lee, H.O., Jordan, C.S., Cantrell, V.A., Southard-Smith, E.M., Shin, M.K. Nat. Genet. (2004)
- The G-netics of dark skin. Jackson, I.J. Nat. Genet. (2004)
- Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution. Nishida, M., MacKinnon, R. Cell (2002)
- The morphologic pathway of exocytosis of the vesicular stomatitis virus G protein in cultured fibroblasts. Wehland, J., Willingham, M.C., Gallo, M.G., Pastan, I. Cell (1982)
- Antisense oligodeoxynucleotides to GS protein alpha-subunit sequence accelerate differentiation of fibroblasts to adipocytes. Wang, H.Y., Watkins, D.C., Malbon, C.C. Nature (1992)
- Augmentation of antigen receptor-mediated responses by histamine H1 receptor signaling. Banu, Y., Watanabe, T. J. Exp. Med. (1999)
- Noncanonical signaling by ionotropic kainate receptors. Rozas, J.L., Paternain, A.V., Lerma, J. Neuron (2003)
- Cloning, expression analysis, and chromosomal mapping of GTPBP2, a novel member of the G protein family. Watanabe, M., Yoshida, K., Hida, M., Kato, H., Uchida, K., Yamaguchi, R., Tateyama, S., Sugano, S. Gene (2000)
- Parental imprinting of the Mas protooncogene in mouse. Villar, A.J., Pedersen, R.A. Nat. Genet. (1994)
- Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Bohn, L.M., Gainetdinov, R.R., Lin, F.T., Lefkowitz, R.J., Caron, M.G. Nature (2000)
- Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Ohta, A., Sitkovsky, M. Nature (2001)
- Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors. Tecott, L.H., Sun, L.M., Akana, S.F., Strack, A.M., Lowenstein, D.H., Dallman, M.F., Julius, D. Nature (1995)
- Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells. Rorsman, P., Bokvist, K., Ammälä, C., Arkhammar, P., Berggren, P.O., Larsson, O., Wåhlander, K. Nature (1991)
- The C5a chemoattractant receptor mediates mucosal defence to infection. Höpken, U.E., Lu, B., Gerard, N.P., Gerard, C. Nature (1996)
- Insulin action impaired by deficiency of the G-protein subunit G ialpha2. Moxham, C.M., Malbon, C.C. Nature (1996)
- Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Conquet, F., Bashir, Z.I., Davies, C.H., Daniel, H., Ferraguti, F., Bordi, F., Franz-Bacon, K., Reggiani, A., Matarese, V., Condé, F. Nature (1994)
- Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling. Inoue, M., Rashid, M.H., Fujita, R., Contos, J.J., Chun, J., Ueda, H. Nat. Med. (2004)
- Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production. Wakelam, M.J., Davies, S.A., Houslay, M.D., McKay, I., Marshall, C.J., Hall, A. Nature (1986)
- Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Contos, J.J., Ishii, I., Fukushima, N., Kingsbury, M.A., Ye, X., Kawamura, S., Brown, J.H., Chun, J. Mol. Cell. Biol. (2002)
- Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform. Sugimoto, N., Takuwa, N., Okamoto, H., Sakurada, S., Takuwa, Y. Mol. Cell. Biol. (2003)
- Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors. Mao, J., Yuan, H., Xie, W., Simon, M.I., Wu, D. J. Biol. Chem. (1998)
- Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway. Coso, O.A., Teramoto, H., Simonds, W.F., Gutkind, J.S. J. Biol. Chem. (1996)
- Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice. Dettlaff-Swiercz, D.A., Wettschureck, N., Moers, A., Huber, K., Offermanns, S. Dev. Biol. (2005)
- Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. Benovic, J.L., Onorato, J.J., Arriza, J.L., Stone, W.C., Lohse, M., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., Caron, M.G., Lefkowitz, R.J. J. Biol. Chem. (1991)
- Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Eckhart, A.D., Duncan, S.J., Penn, R.B., Benovic, J.L., Lefkowitz, R.J., Koch, W.J. Circ. Res. (2000)
- Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C. Diaz-Laviada, I., Larrodera, P., Nieto, J.L., Cornet, M.E., Diaz-Meco, M.T., Sanchez, M.J., Guddal, P.H., Johansen, T., Haro, A., Moscat, J. J. Biol. Chem. (1991)
- Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Slesinger, P.A., Stoffel, M., Jan, Y.N., Jan, L.Y. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Rockman, H.A., Chien, K.R., Choi, D.J., Iaccarino, G., Hunter, J.J., Ross, J., Lefkowitz, R.J., Koch, W.J. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Resistance to thromboembolism in PI3Kgamma-deficient mice. Hirsch, E., Bosco, O., Tropel, P., Laffargue, M., Calvez, R., Altruda, F., Wymann, M., Montrucchio, G. FASEB J. (2001)
- Increased interleukin-6 production in mouse osteoblastic MC3T3-E1 cells expressing activating mutant of the stimulatory G protein. Motomura, T., Kasayama, S., Takagi, M., Kurebayashi, S., Matsui, H., Hirose, T., Miyashita, Y., Yamauchi-Takihara, K., Yamamoto, T., Okada, S., Kishimoto, T. J. Bone Miner. Res. (1998)
- Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without beta1 integrins. Ivanina, T., Neusch, C., Li, Y.X., Tong, Y., Labarca, C., Mosher, D.F., Lester, H.A. FEBS Lett. (2000)
- Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels. Doherty, P., Ashton, S.V., Moore, S.E., Walsh, F.S. Cell (1991)
- Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism. Yu, S., Gavrilova, O., Chen, H., Lee, R., Liu, J., Pacak, K., Parlow, A.F., Quon, M.J., Reitman, M.L., Weinstein, L.S. J. Clin. Invest. (2000)
- Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities. Shin, D.M., Dehoff, M., Luo, X., Kang, S.H., Tu, J., Nayak, S.K., Ross, E.M., Worley, P.F., Muallem, S. J. Cell Biol. (2003)
- Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription. Tremblay, J.J., Drouin, J. Mol. Cell. Biol. (1999)
- Intracellular transport of the transmembrane glycoprotein G of vesicular stomatitis virus through the Golgi apparatus as visualized by electron microscope radioautography. Bergeron, J.J., Kotwal, G.J., Levine, G., Bilan, P., Rachubinski, R., Hamilton, M., Shore, G.C., Ghosh, H.P. J. Cell Biol. (1982)
- Identification and characterization of a mouse cell mutant defective in the intracellular transport of glycoproteins. Tufaro, F., Snider, M.D., McKnight, S.L. J. Cell Biol. (1987)
- Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences. Mitrovic, I., Margeta-Mitrovic, M., Bader, S., Stoffel, M., Jan, L.Y., Basbaum, A.I. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Strathmann, M., Wilkie, T.M., Simon, M.I. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation. Balijepalli, R.C., Foell, J.D., Hall, D.D., Hell, J.W., Kamp, T.J. Proc. Natl. Acad. Sci. U.S.A. (2006)