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Gene Review: 

BTH_I3196  -  flagellin

Burkholderia thailandensis E264

 
 
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Disease relevance of BTH_I3196

  • A simple method to detect and differentiate Burkholderia pseudomallei and Burkholderia thailandensis using specific flagellin gene primers [1].
  • We have previously shown that Burkholderia pseudomallei, the causative pathogen of melioidosis, may be discriminated from the closely related non-pathogenic species Burkholderia thailandensis by the presence of a 15 base pair deletion in the flagellin gene of B. thailandensis [1].
 

Analytical, diagnostic and therapeutic context of BTH_I3196

  • Using specific flagellin gene primers flanking the distinctive region, PCR products of 191 and 176 bp in size were detected for B. pseudomallei and B. thailandensis, respectively [1].

References

  1. A simple method to detect and differentiate Burkholderia pseudomallei and Burkholderia thailandensis using specific flagellin gene primers. Sonthayanon, P., Krasao, P., Wuthiekanun, V., Panyim, S., Tungpradabkul, S. Mol. Cell. Probes (2002) [Pubmed]
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