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Gene Review:

FMO6P - flavin containing monooxygenase 6 pseudogene

Homo sapiens

Synonyms: Dimethylaniline oxidase 6, FMO 6, FMO6, Flavin-containing monooxygenase 6

Hines, R.N. et al., Choi, H.S. et al., Koukouritaki, S.B. et al.

Hines, Hopp, Franco, Saeian, Begun,

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Disease relevance of FMO6P

A novel flavin-containing monooxygenase from Methylophaga sp strain SK1 and its indigo synthesis in Escherichia coli [1].

High impact information on FMO6P

Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants [2].
Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase [3].
When FMO6 expression was examined by reverse transcriptase coupled polymerase chain reaction DNA amplification, transcripts were identified in 8 of 11 human liver samples, but 0 of 4 kidney biopsy samples [3].

References

A novel flavin-containing monooxygenase from Methylophaga sp strain SK1 and its indigo synthesis in Escherichia coli. Choi, H.S., Kim, J.K., Cho, E.H., Kim, Y.C., Kim, J.I., Kim, S.W. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants. Koukouritaki, S.B., Poch, M.T., Cabacungan, E.T., McCarver, D.G., Hines, R.N. Mol. Pharmacol. (2005) [Pubmed]
Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase. Hines, R.N., Hopp, K.A., Franco, J., Saeian, K., Begun, F.P. Mol. Pharmacol. (2002) [Pubmed]

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