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Gene Review

TrpA1  -  Transient receptor potential cation...

Drosophila melanogaster

Synonyms: ANKTM1, Anktm1, Ankyrin-like with transmembrane domains protein 1, CG5751, CG5761, ...
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High impact information on TrpA1

  • We demonstrate dTRPA1, a heat-activated Transient Receptor Potential (TRP) family ion channel, is essential for thermotaxis in Drosophila. dTrpA1 knockdown eliminates avoidance of elevated temperatures along a thermal gradient [1].


  1. The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis. Rosenzweig, M., Brennan, K.M., Tayler, T.D., Phelps, P.O., Patapoutian, A., Garrity, P.A. Genes Dev. (2005) [Pubmed]
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